When it comes to skincare, understanding the difference between ingredients that target the cellular level versus those that address surface-level concerns is essential for achieving both anti-aging and pro-longevity results.
Ingredients Targeting Cellular Level Concerns
NAD+ (Nicotinamide Adenine Dinucleotide):
A crucial coenzyme found in every cell of the body, NAD+ plays an essential role in cellular metabolism and energy production. It helps repair damaged DNA, promotes skin cell turnover, and supports overall skin health, making it a valuable ingredient for enhancing skin longevity (Moore et al., 2022).
NMN (Nicotinamide Mononucleotide):
NMN is a precursor to NAD+, contributing to increasing NAD+ levels within cells. By boosting NAD+ levels, NMN aids in improving skin function and resilience, potentially reducing signs of aging at a cellular level (Yoshino et al., 2018).
NR (Nicotinamide Riboside):
Like NMN, NR is another precursor to NAD+ and has been shown to improve skin vitality by enhancing cellular energy and repair mechanisms (Baur et al., 2007). It helps support the skin’s natural defenses against aging and promotes an overall healthier appearance.
Peptides:
Peptides are short chains of amino acids that serve as building blocks for proteins in the skin, including collagen and elastin. By sending signals to the skin to produce more of these proteins, peptides help to restore elasticity and firmness, targeting the deeper layers of the skin (Kumar et al., 2019).
Growth Factors:
Proteins that are naturally present in the skin can stimulate cellular growth, repair, and regeneration. Growth factor serums can enhance the skin's ability to heal and rejuvenate, promoting a smoother and more even complexion over time (Huh et al., 2021).
Antioxidants (Methylene Blue, Vitamin C, Vitamin E, Coenzyme Q10):
High concentrations of antioxidants work at the cellular level by neutralizing free radicals and reducing oxidative stress that accelerates aging (Pinnell et al., 2001).
Ingredients Addressing Surface-Level Concerns
Hyaluronic Acid:
This powerful humectant draws moisture to the skin and helps keep it hydrated. While it primarily addresses surface dryness and plumpness, it creates an immediate visual improvement in skin texture and elasticity (Papakonstantinou et al., 2012).
Alpha Hydroxy Acids (AHAs) and Beta Hydroxy Acids (BHAs):
AHAs (like glycolic acid) and BHAs (like salicylic acid) exfoliate the surface layer of the skin, removing dead skin cells and improving brightness. They are effective in treating surface-level concerns such as dullness, uneven texture, and clogged pores (López-Estebaranz et al., 2009).
Moisturizers:
Creams and lotions containing occlusive agents (like petrolatum or dimethicone) help to lock in moisture on the surface of the skin, providing immediate relief from dryness and enhancing the skin barrier (Draelos et al., 2008). Additionally, ingredients like squalene mimic natural skin oils, providing intense hydration, locking in moisture and supporting the skin's lipid barrier.
Sunscreens:
While not traditionally anti-aging, sunscreens protect the surface of the skin from UV damage, preventing the breakdown of collagen and elastin, which is crucial for maintaining longevity (Benson et al., 2005).
The Balance for Optimal Longevity
For a comprehensive approach to skincare, it’s essential to incorporate ingredients from both categories. While ingredients targeting the cellular level promote deeper skin health and long-term anti-aging benefits, surface-level products help in achieving immediate results and addressing transient concerns.
By combining these strategies, you can create a well-rounded skincare routine that supports both the appearance and health of your skin, fostering lasting longevity and resilience.
The Renue Blue Skincare range incorporates both surface level and cellular level ingredients for a more comprehensive approach to skin aging and longevity. 